Publication References

Original Peer-Reviewed Articles
1.    Muller JE, Stone PH, Turi Z, et al. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med. 1985; 313:1315-1322.

2.    Muller JE, Ludmer P, Willich S, et al. Circadian variation in the frequency of sudden cardiac death. . Circulation. 1987;75:131-138.

3.    Tofler G, Brezinski D, Schafer A, et al. Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Engl J Med. 1987;316:1514-1518.

4.    Willich S, Levy D, Rocco M, et al. Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population. Am J Cardiol. 1987;60:801-806.

5.    Lodder RA, Hieftje GM, Moorehead W, Robertson SP, Rand P. Assessment of the feasibility of determination of cholesterol and other blood constituents by near-infrared reflectance analysis. Talanta. 1989;36:193-198.

6.    Marler J, Price T, Clark G, et al. Morning increase of stroke onset. Stroke. 1989;20:473-476.

7.    Muller JE, Stone PH. Circadian variation and triggers of onset of acute cardiovascular disease. Circulation. 1989;79:733-743.

8.    Muller JE, Tofler G, Edelman E. Probable triggers of onset of acute myocardial infarction. Clin Cardiol . 1989;12:473.

9.    Lodder RA, Cassis L, Ciurczak EW. Arterial Analysis with a Novel Near-IR Fiber-Optic Probe. Spectroscopy. 1990;5:12-17.

10.    Tofler G, Stone PH, Maclure M, et al. Analysis of possible triggers of acute myocardial infarction (The MILIS Study). Am J Cardiol. 1990;66:22-27.

11.    Willich S, Goldberg R, Maclure M, Perriello L, Muller JE. Increased onset of sudden cardiac death in the first three hours after awakening. Am J Cardiol. 1992;70:65-68.

12.    Cassis LA, Lodder RA. Near-IR imaging of atheromas in living arterial tissue. Anal Chem. 1993;65(9):1247-1256.

13.    Mittleman M, Maclure M, Tofler G, et al. Triggering of acute myocardial infarction by heavy physical exertion: Protection against triggering by regular exertion. N Engl J Med. 1993;329:1677-1683.

14.    Muller JE, Abela G, Nesto R, Tofler G. Triggers, acute risk factors, and vulnerable plaques: The lexicon of a new frontier. J Am Coll Cardiol. 1994;23:809-813.

15.    Mittleman M, Maclure M, Sherwood J, et al. Triggering of acute myocardial infarction onset by episodes of anger. Circulation. 1995;92:1720-1725.

16.    Muller JE, Mittleman M, Maclure M, et al. Triggering of myocardial infarction by sexual activity:  Low absolute risk and prevention by regular physical exertion. . J Am Med Assoc. 1996;275:1405-1409.

17.    Waxman S, Sassower M, Mittleman M, et al. Angioscopic predictors of early adverse outcome after coronary angioplasty in patients with unstable angina and non-Q-wave myocardial infarction. Circulation. 1996;93:2106-2113.

18.    Dempsey RJ, Davis DG, Buice RG, Lodder RA. Biological and Medical Applications of Near-Infrared Spectrometry. Appl Spectrosc. 1996;50:18A-34A.

19.    Waxman S, Mittleman M, Zarich S, et al. Angioscopic assessment of coronary lesions underlying thrombosis. Am J Cardiol. 1997;79:1106-1109.

20.    Jaross W, Neumeister V, Lattke P, Schuh D. Determination of cholesterol in atherosclerotic plaques using near infrared diffuse reflection spectroscopy. Atherosclerosis. 1999;147(2):327-337.

21.    Moreno PR, Muller JE. Identification of high-risk atherosclerotic plaques: a survey of spectroscopic methods. Curr Opin Cardiol. 2002;17(6):638-647.

22.    Neumeister V, Scheibe M, Lattke P, Jaross W. Determination of the cholesterol–collagen ratio of arterial atherosclerotic plaques using near infrared spectroscopy as a possible measure of plaque stability. Atherosclerosis. 2002;165(2):251-257.

23.    Moreno PR, Lodder RA, Purushothaman KR, et al. Detection of Lipid Pool, Thin Fibrous Cap, and Inflammatory Cells in Human Aortic Atherosclerotic Plaques by Near-Infrared Spectroscopy. Circulation. 2002;105(8):923-927.

24.    Wang J, Geng Y, Guo B, et al. Near-infrared spectroscopic characterization of human advanced atherosclerotic plaques. J Am Coll Cardiol. 2002;39(8):1305-1313.

25.    Moreno P, Muller J. Detection of High-Risk Atherosclerotic Coronary Plaques by Intravascular Spectroscopy. J Interv Cardiol. 2003;16(3):243-252.

26.    Urbas A, Manning MW, Daugherty A, Cassis LA, Lodder RA. Near-Infrared Spectrometry of Abdominal Aortic Aneurysm in the ApoE-/- Mouse. Anal Chem. 2003;75(14):3318-3323.

27.    Naghavi M, Libby P, Falk E, et al. From Vulnerable Plaque to Vulnerable Patient: A Call for New Definitions and Risk Assessment Strategies: Part I. Circulation. 2003;108(14):1664-1672.

28.    Moreno PR, Purushothaman KR, Fuster V, et al. Plaque Neovascularization Is Increased in Ruptured Atherosclerotic Lesions of Human Aorta Implications for Plaque Vulnerability. Circulation. 2004;110:2032-2038.

29.    Schaar JA, Muller JE, Falk E, et al. Terminology for high-risk and vulnerable coronary artery plaques. Report of a meeting on the vulnerable plaque, June 17 and 18, 2003, Santorini, Greece. Eur Heart J. 2004;25(12):1077-82.

30.    Bosch JL, Beinfeld MT, Muller JE, Brady T, Gazelle GS. A Cost-Effectiveness Analysis of a Hypothetical Catheter-Based Strategy for the Detection and Treatment of Vulnerable Coronary Plaques with Drug-Eluting Stents. J Interv Cardiol. 2005;18(5):339-349.

31.    Muller JE, Tawakol A, Kathiresan S, Narula J. New Opportunities for Identification and Reduction of Coronary Risk Treatment of Vulnerable Patients, Arteries, and Plaques. J Am Coll Cardiol. 2006;47(8 Suppl C):2-6.

32.    Purushothaman KR, Sanz J, Zias E, Fuster V, Moreno PR. Atherosclerosis Neovascularization and Imaging. Curr Mol Med. 2006;6(5):549-556.

33.    Caplan JD, Waxman S, Nesto RW, Muller JE. Near-Infrared Spectroscopy for the Detection of Vulnerable Coronary Artery Plaques. J Am Coll Cardiol. 2006;47(Suppl_C):C92-C96.

34.    Waxman S, Ishibashi F, Muller JE. Detection and Treatment of Vulnerable Plaques and Vulnerable Patients: Novel Approaches to Prevention of Coronary Events. Circulation. 2006;114(22):2390-2411.

35.    Cheruvu PK, Finn AV, Gardner CM, et al. Frequency and Distribution of Thin-Cap Fibroatheroma and Ruptured Plaques in Human Coronary Arteries : A Pathologic Study. J Am Coll Cardiol. 2007;50(10):940-949.

36.    Waxman S, Ishibashi F, Caplan JD. Rationale and use of near-infrared spectroscopy for detection of lipid-rich and vulnerable plaques. J Nucl Cardiol. 2007;14(5):719-728.

37.    Gardner CM, Tan H, Hull EL, et al. Detection of Lipid Core Coronary Plaques in Autopsy Specimens With a Novel Catheter-Based Near-Infrared Spectroscopy System. J Am Coll Cardiol Img. 2008;1(5):638-648.

38.    Waxman S. Near-Infrared Spectroscopy for Plaque Characterization. J Interv Cardiol. 2008;21(6):452-458.

39.    Waxman S, Khabbaz K, Connolly R, et al. Intravascular imaging of atherosclerotic human coronaries in a porcine model: a feasibility study. The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging). 2008;24(1):37-44.

40.    Waxman S, Simon R. Dixon, L'Allier P, et al. In Vivo Validation of a Catheter-Based Near-Infrared Spectroscopy System for Detection of Lipid Core Coronary Plaques: Initial Results of the SPECTACL Study. J Am Coll Cardiol Img. 2009;2:858-868.

Reviews, Book Chapters, Letters, and Editorials
1.    Muller JE, Moreno PR. Definition of the Vulnerable Plaque. In: Waksman R, Serruys PW, eds. Handbook of the Vulnerable Plaque. Boca Raton, FL: Taylor & Francis; 2004:1-13.

2.    Moreno PR, Marshik B, Muller JE. Diffuse Reflectance Near-Infrared Spectroscopy as a Clinical Technique to Detect High-Risk Atherosclerotic Plaques. In: Waksman R, Serruys PW, eds. Handbook of the Vulnerable Plaque. Boca Raton, FL: Taylor & Francis; 2004:205-218.

3.    Levin S. InfraReDx: Saved by Angels (and a VC). In Vivo: The Business and Medicine Report. 2006;24(4):1-8.

4.    Cheruvu PK, Moreno PR, Marshik BJ, Muller JE. Diffuse reflectance near-infrared spectroscopy as a clinical technique to detect high-risk atherosclerotic plaques. In: Waksman R, Serruys PW, Schaar J, eds. The Vulnerable Plaque. 2nd ed. Informa Health Care; 2007:199-210. 

5.    Urbas AA, Lodder RA. Near-Infrared Spectrometry in Cardiovascular Disease. In: Handbook of Near-Infrared Analysis.; 2007.

6.    Moreno PR, Marshik B, Muller JE. Near-Infrared Spectroscopy. In: Virmani R, Narula J, Leon M, Willerson J, eds. The Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management. Malden, MA: Blackwell Futura; 2007:257-262.

7.    Muller JE, Moreno PR, Cheruvu PK. Definition and Terminology of the Vulnerable Plaque. In: The Vulnerable Plaque. 2nd ed. Informa Health Care; 2007:3-12.

8.    Maini B. Clinical Coronary Chemograms and Lipid Core Containing Coronary Plaques. J Am Coll Cardiol Img. 2008;1(5):689-690.

9.    Young JJ. Detection of Vulnerable Coronary Artery Plaques Lesion Level Risk Assessment Within the Coronary Arterial Tree? J Am Coll Cardiol Img. 2008;1(5):649-651.

10.    Muller JE, Dixon SR. Googling the Coronary: Fiberoptics and a Computer Provide the Answers. J Am Coll Cardiol Img. 2008;1:762-764.

11.    Dixon S. Detecting Vulnerable Plaque. CathLab Digest. 2009;17(3):10.

12.    Sum S, Madden S, Hendricks M, Chartier S, Muller J. Near-infrared spectroscopy for the detection of lipid core coronary plaques. Current Cardiovascular Imaging Reports. 2009;2(4):307-315.

Abstracts
1.    Moreno PR, Lodder RA, O'Conner WN, et al. Characterization of vulnerable plaques by near infrared spectroscopy in an atherosclerotic rabbit model (ACC 1999). J Am Coll Cardiol. 1999;33(Suppl A):A66.

2.    Moreno PR, Purushothaman KR, O’Connor WN, Fuster V, Muller JE. Lack of association between calcification and vulnerability in human atherosclerotic plaques. J Am Coll Cardiol. 2000;35:303A.

3.    Moreno PR, Purushothaman KR, O’Connor WN, et al. Increased neovascularization in disrupted human atherosclerotic plaques. J Am Coll Cardiol. 2000;35:275A.

4.    Charash WE, Lodder RA, Moreno P., et al. Detection of simulated vulnerable plaque using a novel near infrared spectroscopy catheter (ACC 2000). J Am Coll Cardiol 2000; 35 (Suppl A): 38A.

5.    Moreno PR, Ryan SE, Hopkins D, et al. Identification of lipid-rich plaques in human coronary artery autopsy specimens by near-infrared spectroscopy (ACC 2001). J Am Coll Cardiol. 2001; 37 (Suppl A):356A.

6.    Moreno PR, Ryan SE, Hopkins D. Identification of lipid-rich aortic atherosclerotic plaques in living rabbits with a near infrared spectroscopy catheter (ACC 2001). J Am Coll Cardiol. 2001; 37 (Suppl A): 3A.

7.    Marshik B, Tan H, Tang J, et al. Discrimination of lipid-rich plaques in human aorta specimens with NIR spectroscopy through whole blood (TCT 2002). Am J Cardiol 2002; 90 (Suppl 6A).:129H.

8.    Marshik B, Tan H, Tang J, Lindquist A, Zuluaga A. Detection of thin-capped fibroatheromas in human aorta tissue with near infrared spectroscopy through blood (ACC 2003). J Am Coll Cardiol 2003; (Suppl 1):42.

9.    Marshik B, Zulaga A, Tan H. Receiver Operating Characteristics (ROC) Curves Used to Provide Guidance for Model Selection (GRC 2003). Gordon Research Conference 2003.

10.    Zulaga A, DeJesus S. Miniaturized probes for intra-coronary spectroscopy through blood (ACC 2003). J Am Coll Cardiol 2003.

11.    Zuluaga AF, Marshik BJ, Tan H, Tang J, Lindquist AM. Discrimination of lipid-rich atheromas through whole blood using near-infrared reflectance spectroscopy (SPIE Optics East 2003). SPIE 2003; 5141: 260-265.

12.    Waxman S, Khabbaz KR, Connolly RJ, et al. An animal model for in vivo imaging of human coronaries: a new tool to evaluate emerging technologies to detect vulnerable plaques (ACC 2004). J Am Coll Cardiol 2004; 43 (Suppl 2):A73.

13.    Waxman S, Tang J, Marshik BJ, et al. In vivo detection of a coronary artificial target with a near infrared spectroscopy catheter (TCT 2004). Am J Cardiol 2004; 94 (Suppl 6A): 141E.

14.    Waxman S, L'Allier P, Tardif J, et al. Scanning near-infrared (NIR) spectroscopy of coronary arteries for detection of lipid-rich plaque in patients undergoing PCI- Early results of the SPECTACL study (AHA 2006). Circulation 2006; 114: II-647.

15.    Mills TC, Waxman S, Goldstein JA, et al. Initial Results Of Near-Infrared Spectroscopic Scanning Of The Coronary Artery In Patients With Stable Angina (IC 2006). Interventional Cardiology 2006.

16.    Cheruvu PK, Finn AV, Virmani R, et al. Focality and composition of thin cap fibroatheroma, suspected precursors of coronary plaque rupture (TCT 2006) . Am J Cardiol 2006; 98 (8): 36M.

17.    Gardner CM, Tan H, DeJesus S, Caplan JD, Muller JE. Identification of thin-capped fibroatheroma through blood with probe-based near-infrared spectroscopy in human  coronary autopsy specimens (TCT 2006). Am J Cardiol 2006; 98 (8): 222M.

18.    Mills TC, Muller JE. Development of a Near-Infrared Spectroscopy Catheter for Identification of Lipid-Rich Coronary Artery Plaques (IC 2007). Interventional Cardiology 2007.

19.    Waxman S, L’Allier P, Goldstein J, et al. Detection of lipid rich plaque by near infrared spectroscopy (NIRS) in patients undergoing coronary intervention: Results in an unblinded cohort of the SPECTroscopic assessment of coronary lipid (SPECTACL) study (TCT 2007). Am J Cardiol. 2007; 100 (Suppl 1): 231L.

20.    Gardner CM, Lisauskas J, Hull EL, et al. A catheter-based near-infrared scanning spectroscopy system for imaging lipid-rich plaques in human coronary arteries in vivo (SPIE Optics East 2007). Next-Generation Spectroscopic Technologies, SPIE 2007; 6765: 8.

21.    Gardner CM, Tan H, Hull EL, et al. Detection of lipid-rich coronary plaques through blood in autopsy specimens with a novel catheter-based near-infrared spectroscopy system (TCT 2007). Am J Cardiol 2007; 100 (8).

22.    Burka M. Near-infrared spectroscopic detection of lipid core coronary plaques. NESA-OSA 2008.

23.    Dixon SR, L'Allier P, Moses JW, et al. Near-infrared spectroscopic measurement of lipid-core coronary plaque length: implications for complete lesion coverage in patients undergoing stenting (TCT 2008). Am J Cardiol0 2008; 102 (8).

24.    Gardner CM, Hull EL, Lisauskas JB, et al. Use of the block chemogram to interpret the near infrared spectroscopic signs of lipid core containing coronary plaques (TCT 2008). Am J Cardiol 2008; 102 (8).

25.    He Z, Gardner CM, Madden SP, et al. Correlation between the number of lipid core containing plaques identified by a near infrared spectroscopy system and histologic findings (AHA 2008). Circulation 2008; 118: S_744-S_745.

26.    Hull EL, Gardner CM, Madden SP, et al. Assessment of the lipid-burden of human coronary autopsy specimens with a catheter-based near-infrared spectroscopy system: The NIR lipid burden index (ACC 2008). J Am Coll Cardiol 2008; 51 (10).

27.    Hull EL, Gardner CM, Muller VJ, et al. Optical mechanisms for detection of lipid-rich atherosclerotic plaques by near-infrared spectroscopy (SPIE Optics East 2008). Photonic Therapeutics and Diagnostics IV, SPIE 2008; 6842: 68422A-11.

28.    Madden SP, Sum ST, Lisauskas JB, et al. Reproducibility of coronary artery lipid core burden index: implications for trial size and treatment efficacy in serial measurements (CMOD 2008). Critical Markers of Disease 2008.

29.    Madden SP. Near-infrared spectroscopic detection of lipid core coronary plaques (SAS Sept. 23, 2008). Society for Applied Spectroscopy Meeting 2008.

30.    Meese TM, Lisauskas JB, Doucet CM, et al. Lipid-rich plaque adjacent to stenosis in coronary autopsy specimens: implications for selection of stent length (ACC 2008). J Am Coll Cardiol 2008; 51 (10).

31.    Petersen JL, Weisz G, Dixon SR, et al. Relationship of the near infrared lipid core burden index in coronary segments with traditional risk factors in patients undergoing PCI (TCT 2008). Am J Cardiol 2008; 102 (8).

32.    Waxman S. Near infrared spectroscopy: clinical update from the spectroscopic assessment of coronary lipid (SPECTACL) pivotal study (CRT 2008). Cardiovascular Revascularization Medicine 2008.

33.    Waxman S. Near infrared spectroscopy for plaque characterization: algorithm development and update from the SPECTroscopic Assessment of Coronary Lipid (SPECTACL) study (ACC 2008). J Am Coll Cardiol 2008.

34.    Meese TM, Lisauskas JB, Doucet CM, et al. Spectroscopic identification of lipid-rich plaques causing intermediate stenosis: a study in coronary autopsy specimens (CRT 2008). Cardiovascular Revascularization Medicine 2008; 9 (2):108.

35.    Weisz G. Identification of lipid core plaques in coronary arteries with NIR spectroscopy (ICI 2008). Innovations in Cardiovascular Interventions 2008.

36.    Weisz G, Dixon SR, Moses JW, et al. Lipid rich plaque identified by near infrared spectroscopy is associated with plaque shift in bifurcation lesions: An observation from the SPECTACL study (TCT 2008). Am J Cardiol 2008; 102 (8).

37.    Goldstein JA, Dixon SR, L'Allier P, et al. Near-infrared spectroscopic detection of lipid core coronary plaques remote from the target lesion in patients undergoing PCI (ACC 2009). J Am Coll Cardiol 2009.

38.    Hull EL, Doucet CM, Gardner CM, et al. Improved characterization of coronary plaques by the use of both near-infrared spectroscopy and grayscale intravascular ultrasound (SCAI 2009). The Society for Cardiovascular Angiography and Interventions Meeting 2009.

39.    L'Allier P, Tardif J, Dixon SR, et al. Frequency of lipid core plaque as determined by near-infrared spectroscopy at target lesion sites in patients undergoing PCI (ACC 2009). J Am Coll Cardiol 2009.

40.    Madden SP, Muller JE. The use of NIR spectroscopic identification of coronary lipid core plaque to facilitate evaluation of novel therapies (CRT 2009). Cardiovascular Revascularization Medicine 2009.

41.    Madden SP, Muller JE. Pathology, Detection and Treatment of Vulnerable Plaque (ISA 2009). XV International Symposium on Atherosclerosis Meeting 2009.

42.    Madden SP, Gardner CM, Hull EL, et al. Multi-Vessel Distribution of ex vivo Lipid Core Burden Index Measurements (SCAI 2009). The Society for Cardiovascular Angiography and Interventions Meeting 2009.