Intravascular NIRS imaging can identify patients and plaques at risk for NC-MACE during a 24-month period.
A total of 1,271 patients were imaged at baseline and followed for 24 months for future NC-MACE.
The co-primary endpoints assessed maxLCBI4mm as a continuous variable using time-to-event Cox proportional hazard models. The key secondary endpoints were assessed with the maxLCBI4mm dichotomized at 400.
The analysis unit for both index procedure analysis and event adjudication was defined by paired standardized 30 mm segments (Proximal, Mid, Distal, and Far Distal).
Vulnerable Patient-Level Analysis
MaxLCBI4mm was computed from all eligible non-culprit scanned area NC-MACE evaluated at a patient level
Vulnerable Plaque-Level Analysis
Evaluation was conditional on the Patient-Level being met
MaxLCBI4mm was computed in each eligible Ware segments
NC-MACE evaluated only in corresponding segments where imaging occurred
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